Article from iAdvance Senior Care
You’ve seen the alarming statistics: there are an estimated 100,000 deaths[i] and upwards of two million serious adverse drug reactions (ADRs) in the United States each year related to prescription drug use, costing the healthcare industry in excess of $136 billion annually according to the Food and Drug Administration. Older individuals are particularly at risk for ADRs due to polypharmacy, co-morbidities and a host of age-related variables and physiological changes that alter drug absorption and metabolism.
Genetic factors can also have a significant influence on drug response, which is estimated to account for 20 to 40 percent of inter-individual differences in drug metabolism and response.[ii] Patients with specific genetic variations are at increased risk from taking many widely prescribed drugs such as common anticoagulants, pain medications and antipsychotics.